Prescription of antibiotics after tooth extraction in adults: a nationwide study in Korea
Journal of the Korean Association of Oral and Maxillofacial Surgeons
;
: 49-57, 2020.
Article
in English
| WPRIM
| ID: wpr-811269
ABSTRACT
OBJECTIVES:
This study aimed to understand the nationwide patterns of antibiotic prescription after tooth extraction in adult patients.MATERIALS ANDMETHODS:
This study analyzed dental records from the National Health Insurance Service–National Sample Cohort (NHIS–NSC) database on 503,725 tooth extractions performed in adults (≥19 years) during 2011–2015. Patient sex, age, household income, systemic disease (diabetes mellitus and hypertension), type of dental institution, region of dental institution, year of prescription, and type of tooth extraction procedure were considered. The antibiotic prescription rate and broad-spectrum antibiotic prescription frequency were analyzed using chi-squared tests. Factors affecting the prescription of broad-spectrum antibiotics were evaluated using multivariate logistic regression analysis.RESULTS:
The rate of antibiotic prescription after tooth extraction was 81.85%. Penicillin was most commonly prescribed (45.25%), followed by penicillin with beta-lactamase inhibitors (18.76%), metronidazole (12.29%), and second- to fourth-generation cephalosporins (11.52%). The proportion of broad-spectrum antibiotics used among all prescribed antibiotics was 45.88%.CONCLUSION:
The findings of this study demonstrate that the rate of antibiotic prescription after tooth extraction is higher in Korea than in other countries. Furthermore, broad-spectrum antibiotics are used more frequently, which may indicate unnecessary drug prescription, an important contributor to antibiotic resistance.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Penicillins
/
Drug Prescriptions
/
Tooth
/
Tooth Extraction
/
Drug Resistance, Microbial
/
Logistic Models
/
Cephalosporins
/
Dental Records
/
Family Characteristics
/
Cohort Studies
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Journal of the Korean Association of Oral and Maxillofacial Surgeons
Year:
2020
Type:
Article
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