Case of a Cystic Hypersecretory Duct Carcinoma of the Breast
Journal of the Korean Surgical Society
;
: 247-251, 2002.
Article
in Korean
| WPRIM
| ID: wpr-81202
ABSTRACT
Breast cystic hypersecretory duct carcinomas (CHDC), characterized by cystic dilatation of ducts, cysts filled with thyroid colloid-like eosinophilic material, and by micropapillary carcinomas in the epithelium lining the cyst, is a rare histological variant of intraductal carcinomas. CHDC is differentiated from cystic hypersecretory hyperplasia. It's clinical manifestations are similar to those of other intraductal carcinomas. CHDC has a low-grade behavior for many years, but can be invasive, with the potential for metastasis. The importance of CHDC is its differentiation from a variety of other lesions of the breast, both benign and malignant. Various differential diagnoses for CHDC include fibrocystic changes of the breast with microcyst formation, juvenile papillomatosis, benign mucocele-like lesions, juvenile secretory carcinomas, mucin-producing colloid carcinomas and metastatic follicular thyroid carcinomas. Histochemical staining (PAS, alcian blue and mucicarmine) or immunoperoxidase studies (CEA, alpha-lactalbumin and thyroglobulin) may also helpful in differential diagnoses. We report a case of a cystic hypersecretory duct carcinoma (CHDC) of the breast, and present a review of the literature.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Papilloma
/
Thyroid Gland
/
Breast
/
Breast Neoplasms
/
Adenocarcinoma, Follicular
/
Carcinoma, Intraductal, Noninfiltrating
/
Adenocarcinoma, Mucinous
/
Breast Cyst
/
Diagnosis, Differential
/
Dilatation
Type of study:
Diagnostic study
Language:
Korean
Journal:
Journal of the Korean Surgical Society
Year:
2002
Type:
Article
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