Two new phragmalin-type limonoids orthoesters from Entandrophragma candollei / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 680-683, 2017.
Article
in English
| WPRIM
| ID: wpr-812068
ABSTRACT
Two new phragmalin-type limonoids orthoesters, encandollens A and B (1 and 2), were isolated from the stem barks of Entandrophragma candollei collected in Ghana. The structures of these compounds were elucidated on the basis of HR-ESI-MS, H and C NMR, HSQC, HMBC, and ROESY data. Compound 1 was a rare C-15 enolic acyl phragmalin-type limonoid orthoester. Compounds 1 and 2 exhibited weak inhibitory effects on NO production in lipopolysaccharide (LPS)-induced RAW 264.7 cells.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Drugs, Chinese Herbal
/
Molecular Structure
/
Chemistry
/
Meliaceae
/
Plant Bark
/
Limonins
/
Macrophages
/
Metabolism
/
Nitric Oxide
Limits:
Animals
Language:
English
Journal:
Chinese Journal of Natural Medicines (English Ed.)
Year:
2017
Type:
Article
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