A lignin glycoside and a nortriterpenoid from Kadsura coccinea / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 782-785, 2014.
Article
in English
| WPRIM
| ID: wpr-812200
ABSTRACT
AIM@#To study the chemical constituents of the roots and stem bark of Kadsura coccinea.@*METHOD@#Compounds were isolated by column chromatography on silica gel and Sephadex LH-20, and finally purified by prep-HPLC. Their structures were elucidated by extensive spectroscopic methods, including 1D- and 2D-NMR, and HR-ESI-MS.@*RESULTS@#Two compounds were determined as (7'S,8'S,8R)-(8β,8'α)-dimethyl-4,4'-dihydroxy-5,3'-dimethoxy-5'-cyclolignan glucoside (1) and micrandiactone H (2), respectively.@*CONCLUSION@#Compunds 1 and 2 are new and neither showed inhibitory effects on nitric oxide (NO) production in lipopolysaccharide-induced RAW264.7 macrophages.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Mass Spectrometry
/
Plant Extracts
/
Magnetic Resonance Spectroscopy
/
Molecular Structure
/
Cell Line
/
Chemistry
/
Plant Roots
/
Kadsura
/
Glycosides
Limits:
Animals
Language:
English
Journal:
Chinese Journal of Natural Medicines (English Ed.)
Year:
2014
Type:
Article
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