A new sesquiterpene lactone from the fruits of Illicium henryi / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
; (6): 477-480, 2014.
Article
in En
| WPRIM
| ID: wpr-812245
Responsible library:
WPRO
ABSTRACT
AIM@#To study the chemical constituents of the fruits of Illicium henryi.@*METHOD@#Chromatographic separations on silica gel, Sephadex LH-20 gel and MCI gel were used to isolate the compounds. The structures were elucidated based on extensive spectroscopic data analyses.@*RESULTS@#Seven compounds were obtained and their structures were identified as 10-benzoyl-cycloparvifloralone (1), cycloparvifloralone (2), 2α-hydroxycycloparviforalone (3), henrylactone B (4), merrillianone (5), henrylactone C (6) and 7, 14-ortholactone- 3-hydroxyfloridanolide (7).@*CONCLUSION@#Compound 1 is a new sesquiterpene lactone. The tested compounds showed weak anti-HBV activities on HBV surface antigen (HBsAg) secretion and HBV e antigen (HBeAg) secretion using Hep G2.2.15 cell line.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Antiviral Agents
/
Pharmacology
/
Sesquiterpenes
/
Plant Extracts
/
Molecular Structure
/
Chemistry
/
Hepatitis B virus
/
Illicium
/
Hep G2 Cells
/
Fruit
Limits:
Humans
Language:
En
Journal:
Chinese Journal of Natural Medicines (English Ed.)
Year:
2014
Type:
Article