Structure and antibacterial property of a new diterpenoid from Euphorbia helioscopia / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 704-706, 2015.
Article
in English
| WPRIM
| ID: wpr-812492
ABSTRACT
The present study was designed to isolate and evaluate the antibacterial activity of the compounds from the whole plant of Euphorbia helioscopia L.. Various chromatographic techniques were used to isolate and purify the compound. The structure of the compound was elucidated on basis of spectral data ((1)H NMR, (13)C NMR, (1)H-(1)H COSY, HSQC, HMBC, NOESY, IR, and HR-ESI-MS). A new jatrophone-type diterpenoid (14α,15β-diacetoxy-3β-benzoyloxy-7β-nicotinoyloxy-9-oxo-jatropha-5E,11E-diene), named euphoheliosnoid E (1), was isolated from the whole plant of E. helioscopia L. Compound 1 showed significant anti-microbial activity against oral pathogens.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Plant Extracts
/
Molecular Structure
/
Chemistry
/
Euphorbia
/
Diterpenes
/
Microbiology
/
Anti-Infective Agents
/
Mouth Diseases
/
Niacin
Language:
English
Journal:
Chinese Journal of Natural Medicines (English Ed.)
Year:
2015
Type:
Article
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