A Case of Etoposide Therapy in a Patient Newly Diagnosed with Classic Kaposi's Sarcoma and Rheumatoid Arthritis / 대한내과학회지
Korean Journal of Medicine
;
: 247-252, 2014.
Article
in Korean
| WPRIM
| ID: wpr-81269
ABSTRACT
Kaposi's sarcoma typically occurs in immunocompromised patients, especially those with acquired immunodeficiency syndrome. Human herpesvirus 8 (HHV-8) and human immunodeficiency virus (HIV) may play important roles in the development of Kaposi's sarcoma. We report the case of a 75-year-old male who presented with progressive multiple purplish papules and nodules on the skin for 3 months. Social and past medical histories seemed incompatible with an immunesuppressed condition and tests for HIV antibodies and HHV-8 were negative. He was newly diagnosed with rheumatoid arthritis, according to the 2010 ACR-EULAR criteria. Typical findings of Kaposi's sarcoma were confirmed by biopsy. After treatment with metronomic oral etoposide 25 mg once daily for 9 months, the skin lesions had almost resolved with no serious complication. Thus, we report a rare case of Kaposi's sarcoma developing in a patient with newly diagnosed rheumatoid arthritis who showed a good response to oral etoposide.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arthritis, Rheumatoid
/
Sarcoma, Kaposi
/
Skin
/
Biopsy
/
HIV Antibodies
/
Acquired Immunodeficiency Syndrome
/
HIV
/
Immunocompromised Host
/
Herpesvirus 8, Human
/
Etoposide
Type of study:
Diagnostic study
Limits:
Aged
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2014
Type:
Article
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