A new isoflavonoid glycoside from the aerial parts of Trachelospermum jasminoides / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 274-276, 2013.
Article
in English
| WPRIM
| ID: wpr-812693
ABSTRACT
AIM@#To study the chemical constituents from the aerial parts of Trachelospermum jasminoides.@*METHODS@#Compounds were isolated by various chromatographic methods and their structures were elucidated on the basis of spectral techniques. In addition, the inhibitory activity against HepG2 and HL-60 of compound 1 was evaluated.@*RESULTS@#Five compounds were isolated and identified as 3', 7-dimethoxyisoflavanone-4', 5-di-O-β-D-glucopyranoside (1), tracheloside (2), nortrachelogenin 5'-C-β-glucopyranoside (3), luteolin-4'-O-β-D-rutinoside (4), and luteolin-7-O-β-D-glucopyranoside (5).@*CONCLUSION@#Compound 1 is a new isoflavonoid glycoside. It showed weak inhibitory activity against HepG2 and HL-60 cancer cells with IC50 values of 131.5 and 58.2 μmol·L(-1), respectively.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Flavonoids
/
Plant Extracts
/
Molecular Structure
/
Chemistry
/
Apocynaceae
/
Plant Components, Aerial
/
Cell Line, Tumor
/
Cell Proliferation
/
Glycosides
Limits:
Humans
Language:
English
Journal:
Chinese Journal of Natural Medicines (English Ed.)
Year:
2013
Type:
Article
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