Microdissection testicular sperm extraction for patients with nonmosaic Klinefelter syndrome: A report of 143 cases / 中华男科学杂志
National Journal of Andrology
;
(12): 1075-1079, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-812832
ABSTRACT
Objective@#To investigate the clinical application and outcomes of microdissection testicular sperm extraction (micro-TESE) in patients with nonmosaic Klinefelter syndrome (KS).@*METHODS@#A total of 143 nonmosaic KS patients underwent micro-TESE in the Center of Reproductive Medicine of Peking University Third Hospital between July 2012 and August 2016. We analyzed their clinical and follow-up data and evaluated the outcomes.@*RESULTS@#Spermatozoa were successfully retrieved from the testicular tissue in 44.76% (64/143) of the patients, 84.4% (54/64) by unilateral and 15.6% (10/64) by bilateral micro-TESE. Seventy-five of the KS patients were followed up in the years of 2014 and 2015. Of the 34 patients with successful sperm retrieval, 73.52% (25/34) achieved clinical pregnancy and 8 boys and 8 girls were already born in 14 of the 25 cases.@*CONCLUSIONS@#The micro-TESE is a useful method for sperm retrieval in nonmosaic KS patients, with high rates of sperm retrieval, clinical pregnancy, and birth of biological offspring.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Spermatozoa
/
Testis
/
Pregnancy Rate
/
Sperm Injections, Intracytoplasmic
/
Microdissection
/
Sperm Retrieval
/
Klinefelter Syndrome
Limits:
Female
/
Humans
/
Male
/
Pregnancy
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2017
Type:
Article
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