Correlation of serum zinc alpha 2 glycoprotein with blood lipid and reproductive hormone levels in men / 中华男科学杂志
National Journal of Andrology
;
(12): 997-1001, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-812843
ABSTRACT
Objective@#To study the changes of the serum zinc alpha 2 glycoprotein (ZAG) level in men and its relationship with blood lipid male reproductive hormones.@*METHODS@#We enrolled 297 men aged 25- 65 years in this study, 152 with hyperlipemia (HL) and the other 145 with normal blood lipid (normal control). We divided them into four age groups (25-35 yr, 36-45 yr, 46-55 yr, and 56-65 yr) and three tertile groups (Q1, Q2, and Q3) according to the tertiles of the serum ZAG level, and examined their blood lipid, blood glucose, serum ZAG, and reproductive hormones.@*RESULTS@#The serum ZAG level was decreased gradually with the increase of age in both the HL patients and normal controls, significantly in the 36-45 and 56-65 yr age groups (P <0.05), and markedly lower in the HL than in the control men in the 25-35 and 36-45 yr groups (P <0.05). The levels of follicle-stimulating hormone (FSH) and total testosterone (TT) changed significantly with the ZAG level. The level of serum ZAG was correlated negatively with age (r = -0.58, P<0.05), waist circumference (r = -0.21, P <0.05), body mass index (BMI) (r = -0.22, P <0.05), fasting blood glucose (r = -0.16, P <0.05) , and triglyceride (TG) (r = -0.27, P <0.05) but positively with TT (r = 0.36, P <0.05). Age, BMI and TG were independent factors influencing the serum ZAG level.@*CONCLUSIONS@#The serum ZAG level is decreased with the increase of age and associated with lipid metabolism, abdominal obesity, and reproductive hormone levels in males.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Reproduction
/
Gonadal Steroid Hormones
/
Triglycerides
/
Blood
/
Blood Glucose
/
Body Mass Index
/
Age Factors
/
Seminal Plasma Proteins
/
Obesity, Abdominal
/
Follicle Stimulating Hormone
Limits:
Adult
/
Aged
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2017
Type:
Article
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