Topical application of clobetasol propionate cream in the treatment of phimosis in prepubertal children: A report of 237cases / 中华男科学杂志
National Journal of Andrology
;
(12): 635-638, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-812903
ABSTRACT
Objective@#To investigate the clinical effect of 0.02% clobetasol propionate cream (CPC) on phimosis in prepubertal children.@*METHODS@#We retrospectively analyzed the clinical data about 237 prepubertal children with phimosis present at the Outpatient Department from June 2012 to December 2015. The patients were aged 2-14 (mean 8.6) years, all treated by topical application of 0.02% CPC to the narrowed opening and adhered part of the foreskin twice a day, in the morning and evening respectively. At the time of CPC application, the foreskin was slightly retracted. We evaluated the therapeutic effect every week from the end of the first week of treatment.@*RESULTS@#Totally, 233 of the patients completed the 8-week treatment, of whom 181 (77.68%) showed full retraction of the foreskin, 28 (12.01%) experienced improvement (disappearance of the phimotic ring), and 24 (10.30%) failed to respond, with a total effectiveness rate of 89.70%. No significant local or systemic adverse reactions were observed during the treatment.@*CONCLUSIONS@#Topical application of 0.02% Clobetasol Propionate Cream is a safe, effective, painless, and inexpensive option for the treatment of phimosis in prepubertal chilodren.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Outpatients
/
Phimosis
/
Clobetasol
/
Retrospective Studies
/
Administration, Topical
/
Treatment Outcome
/
Drug Therapy
/
Foreskin
/
Gels
/
Anti-Inflammatory Agents
Type of study:
Observational study
Limits:
Adolescent
/
Child
/
Child, preschool
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2017
Type:
Article
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