Alzheimer's disease and nerve growth factor gene therapy / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 1413-1418, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-812999
ABSTRACT
Gene therapy plays an important role in Alzheimer's disease (AD). In recent years, the research on gene delivery vector has gradually transferred from adenovirus vector, adeno-associated virus vector and lentivirus vector to liposomes and nanomaterial carrier systems. Graphene, the newest member of nanomaterial carrier system, has attracted extensive attention for its well permeability and biocompatibility. The methods of gene therapy can be divided into direct and indirect method. The stem cell therapy, which is the most-well studied one, belongs to the indirect method. In the gene therapy of AD, the selection of appropriate carrier and method will determine the therapeutic effect.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Therapeutics
/
Genetic Therapy
/
Gene Transfer Techniques
/
Dependovirus
/
Alzheimer Disease
/
Genetic Vectors
Limits:
Humans
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2019
Type:
Article
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