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Salivary cortisol level and peri-abortion depression / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences) ; (12): 1023-1029, 2019.
Article in Chinese | WPRIM | ID: wpr-813054
ABSTRACT
To study the salivary cortisol level, and to analyze the correlation between salivary cortisol and peri-abortion depression in the women suffering termination of pregnancy for fetal anomaly.


Methods:

Comparing the difference in salivary cortisol level between the women with and without depression when they underwent termination of pregnancy for fetal anomaly in a prospective cohort study. Analyzing the correlation between salivary cortisol and peri-abortion depression through logistics regression analysis.


Results:

The salivary cortisol awakening response was lower in women with depression than women without depression. Based on the logistics regression analysis, the salivary cortisol awakening response showed a negative correlation with pre-abortion (OR=0.063, 95% CI 0.005 to 0.754) and post-abortion (OR=0.002, 95% CI 0.000 to 0.061) depression.


Conclusion:

Cortisol awakening response possesses a negative correlation with peri-abortion depression, and it is a predictive factor for post-abortion depression.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Saliva / Hydrocortisone / Prospective Studies / Depression / Depressive Disorder / Metabolism Type of study: Observational study / Prognostic study / Risk factors Limits: Female / Humans / Pregnancy Language: Chinese Journal: Journal of Central South University(Medical Sciences) Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Saliva / Hydrocortisone / Prospective Studies / Depression / Depressive Disorder / Metabolism Type of study: Observational study / Prognostic study / Risk factors Limits: Female / Humans / Pregnancy Language: Chinese Journal: Journal of Central South University(Medical Sciences) Year: 2019 Type: Article