Evaluation of tumor necrosis factor-alpha and tumor necrosis factor-beta in serum of patients with endometriosis / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 304-306, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-813376
ABSTRACT
OBJECTIVE@#To evaluate the levels of tumor necrosis factor-alpha (TNF-alpha) and tumor necrosis factor-beta (TNF-beta) before and after conservative laparoscopic surgery in patients with endometriosis.@*METHODS@#The levels of TNF-alpha and TNF-beta in the serum of both 82 patients with EMS and 68 controls were determined by ELISA.@*RESULTS@#The levels of TNF-alpha and TNF-beta in the serum of patients with EMS were significantly higher than those of the controls (P < 0.01), and they increased with the clinical terms ( P < 0.05). After clearance of endometrosis foci with laparoscopic conservative surgery, the TNF-alpha levels decreased significantly in EMS III - IV, and TNF-beta levels decreased significantly in EMS I - IV.@*CONCLUSION@#Measuring TNF-alpha and TNF-beta levels in the serum of patients with EMS may have important value in postoperative follow-up, surveillance and evaluation of the effectiveness of the surgery.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
General Surgery
/
Blood
/
Follow-Up Studies
/
Lymphotoxin-alpha
/
Tumor Necrosis Factor-alpha
/
Laparoscopy
/
Endometriosis
/
Metabolism
Type of study:
Observational study
/
Prognostic study
Limits:
Adolescent
/
Adult
/
Female
/
Humans
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2005
Type:
Article
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