Pathogenic characters of infected bacteria after liver transplantation / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 430-432, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-813542
ABSTRACT
OBJECTIVE@#To analyze the main pathogens of infection after the liver transplantation and their antibiotic resistant patterns.@*METHODS@#The main pathogens of infection after the liver transplantation were retrospectively analyzed. Using 3-dimensional tests, ESBLs (extended-spectrum beta-lactamase), and AmpC were detected among the Gram negative bacilli. beta-Lactamase and Van gene in Enterococcus were determined by the standard agar dilution susceptibility tests and Nitrocefin respectively.@*RESULTS@#The main infected strains were Enterococcus faecalis (15.0%), Enterobacter cloacae (13.9%), fungus (13.3%), and Escherichia coli (10.7%) after the liver transplantation. Among them, 32.4% of Enterobacter cloacae and 36.8% of Escherichia coli produced ESBLs; 33.8% of Enterobacter cloacae and 10.5% of Escherichia coli. produced AmpC beta-lactamases. The detectable rate of VanA gene in Enterococcusfaecalis and Enterococcus faecium was 7.5% and 11.1%; VanB was 3.8% and 7.4%; VanC was 1.3% and 0, respectively.@*CONCLUSION@#The infection mainly occurs in the intestinal tract after the liver transplantation. The production of ESBLs and AmpC beta-lactamases is the main mechanism of antibiotic resistance. The increased detectable rate of vancomycin-resistant Enterococcus should be paid attention to.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Postoperative Complications
/
General Surgery
/
Microbial Sensitivity Tests
/
Retrospective Studies
/
Liver Transplantation
/
Vancomycin Resistance
/
Drug Resistance, Bacterial
/
Enterobacteriaceae
/
Enterobacteriaceae Infections
/
Genetics
Type of study:
Observational study
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2005
Type:
Article
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