Determination of diltiazem hydrochloride injection by high-performance liquid chromatography / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 756-758, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-813605
ABSTRACT
OBJECTIVE@#To establish an high-performance liquid chromatography (HPLC) method for the determination of diltiazem hydrochloride injection.@*METHODS@#The assay was conducted on a NUCLEODUR C18 column with buffer solution (pH6.2)-acetonitrile-methanol (403030) as the mobile phase and the detection wavelength was 240 nm.@*RESULTS@#Diltiazem hydrochloride and relevant substances could be separated under the condition. The linear concentration range of diltiazem hydrochloride was 4 - 200mg/L with the recovery of 100.22% (RSD = 0.37%).@*CONCLUSION@#The method may be used for the determination of diltiazem hydrochloride injection.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Calcium Channel Blockers
/
Diltiazem
/
Chromatography, High Pressure Liquid
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2006
Type:
Article
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