Measurement of activated clotting time during cardiopulmonary bypass in infective endocarditis patients / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 167-169, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-813914
ABSTRACT
OBJECTIVE@#To investigate the proper dosage of heparin and protamin in treating the patients with infective endocarditis (IE) during the operation.@*METHODS@#Activated clotting time (ACT) was measured during and after cardiopulmonary bypass (CPB) in 30 patients with IE and 30 patients with rheumatic heart disease (RHD) respectively.@*RESULTS@#The dosage of heparin before bypass in IE group was significantly higher than that of RHD group (P0.05).@*CONCLUSION@#The dosage of protamin should be increased to 3 mg/kg as the heparin is over 400 U/kg before CPB in the patient with IE, but the ratio of protamin and heparin will not be obviously changed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
General Surgery
/
Whole Blood Coagulation Time
/
Heparin
/
Protamines
/
Cardiopulmonary Bypass
/
Drug Monitoring
/
Therapeutic Uses
/
Dose-Response Relationship, Drug
/
Endocarditis
/
Heparin Antagonists
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2007
Type:
Article
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