Accessory gene regulator in Staphylococcus biofilm formation and infection / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 1066-1070, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-814149
ABSTRACT
The most important factor in the pathogenesis of biomaterial-associated Staphylococcal infections is the formation of bacterial biofilms. Biofilm formation was regulated or influenced by quorum sensing. One of the quorum sensing systems agr is genus specific which controls the expression of a series of toxins and virulence factors and the interaction with the innate immune system. New research indicates that the role of agr during infection is controversial. The research progress will play an important role in the development of novel antibacterial agents and management of device-related infection of Staphylococci.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Staphylococcal Infections
/
Staphylococcus
/
Bacterial Proteins
/
Biocompatible Materials
/
Signal Transduction
/
Gene Expression Regulation, Bacterial
/
Trans-Activators
/
Biofilms
/
Genetics
Limits:
Humans
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2008
Type:
Article
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