Effect of antipsychotic drugs on life quality of schizophrenic patients: one year follow-up study / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 850-855, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-814209
ABSTRACT
OBJECTIVE@#To compare the effect of 7 antipsychotic drugs on the life quality of schizophrenia patients including chlorpromazine, sulpiride, clozapine, risperidone, olanzapine, quetiapine, and aripiprazole.@*METHODS@#A total of 1,227 stable schizophrenic patients within 5 years onset who took 1 of the 7 study medications as maintenance treatment were followed up for 1 year at 10 China sites. Patients were evaluated by the short form-36 health survey (SF-36) at the baseline and at the end of 1 year.@*RESULTS@#The life quality was improved obviously at the end of the follow-up. There was significant difference in body pain, vitality, and mental health (P<0.05) among these antipsychotic drugs.@*CONCLUSION@#All 7 antipsychotic drugs can improve the life quality of schizophrenia patients. Atypical antipsychotic drugs, especially olazapine and quetiapine, are superior to typical antipsychotic drugs in improving life quality.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Quality of Life
/
Schizophrenia
/
Antipsychotic Agents
/
Benzodiazepines
/
Surveys and Questionnaires
/
Follow-Up Studies
/
Therapeutic Uses
/
Dibenzothiazepines
/
Drug Therapy
/
Quetiapine Fumarate
Type of study:
Observational study
/
Prognostic study
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2009
Type:
Article
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