Analysis of adverse drug reaction of gatifloxacin in Hunan province from Aug. 2003 to Jul. 2007 / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 49-53, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-814253
ABSTRACT
OBJECTIVE@#To summarize the occurrences of adverse drug reactions (ADR) of gatifloxacin, and to guide the rational usage of antibacterial agents in clinical practice in the future.@*METHODS@#A total of 1 077 ADR patient who received gatifloxacin were retrospectively studied in Hunan province from August 2003 to July 2007.@*RESULTS@#Gatifloxacin could cause multi-system and multi-organ ADRs with wide variety of clinical manifestations. Of the 1 077 ADR patients, ADR incidence rate was slightly lower in males than that in females, the age of 821 (76.23%) ADR patients were 20 approximately 59 years; 905 (84.03%) were administered intravenously; and 682 (33.07%) had severe lesions of the digestive system, followed by lesions of the skin and the appendants (490 cases, 23.76%) and the nervous system (298 cases, 14.45%).@*CONCLUSION@#ADR caused by gatifloxacin should be monitored and reported so as to reduce or avoid ADR.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
China
/
Retrospective Studies
/
Adverse Drug Reaction Reporting Systems
/
Fluoroquinolones
/
Drug-Related Side Effects and Adverse Reactions
/
Gatifloxacin
/
Anti-Infective Agents
Type of study:
Observational study
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2009
Type:
Article
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