Propranolol in the treatment of problematic infantile hemangiomas / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 1102-1105, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-814469
ABSTRACT
OBJECTIVE@#To evaluate the short-term efficacy and safety of propranolol for problematic infantile hemangiomas.@*METHODS@#Oral propranolol was administered to 68 infants with heamngiomas diagnosed by clinical evaluation and adjuvant examination at 1.0~2.0 mg per kilogram of body weight per day, divided to 2 or 3 times. The patients revisited once a month. The changes of the tumor size, texture, and color were monitored and recorded at a regular interval.The adverse effects after medication were observed and managed accordingly.The short-term results were evaluated using a 4-grade system.@*RESULTS@#All the 68 infants were followed up for 3-13 months, except that 1 infants combined with other diseases and 4 withdrew.The overall response was Scale 1 in 8 infants, Scale II in 13, Scale III in 29, and Scale IV in 13. No serious adverse effects were seen, but none cured entirely as well.@*CONCLUSION@#Oral propranolol is safe and effective for infantile heamngioma with good short-term result. It could be used as the primary drug for problematic infantile hemangiomas at the rapid growth stage of hemangiomas.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Propranolol
/
Skin Neoplasms
/
Prospective Studies
/
Subcutaneous Tissue
/
Therapeutic Uses
/
Drug Therapy
/
Hemangioma
Type of study:
Observational study
Limits:
Female
/
Humans
/
Infant
/
Male
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2011
Type:
Article
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