Genetics of autism spectrum disorders / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 703-711, 2011.
Article
in English
| WPRIM
| ID: wpr-814530
ABSTRACT
Autism is a group of etiology and clinical heterogeneous neurodevelopmental disorders with an onset before 3 years old. It has 3 core characteristics deficits in verbal communication; impairment of social interaction; restricted interests and repetitive behaviors. The incidence is increasing over time worldwide. Twin and family studies have demonstrated that autism has a high heritability (>90%). Although certain progress of autism genetic study has been made in the last decades and several autism susceptibility genes and loci have been identified, there are still about 70%-80% of patients for whom an autism-related genetic change cannot be identified.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Autistic Disorder
/
Genetic Heterogeneity
/
Epigenomics
/
Genetics
Type of study:
Prognostic study
Limits:
Child, preschool
/
Humans
/
Infant
Language:
English
Journal:
Journal of Central South University(Medical Sciences)
Year:
2011
Type:
Article
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