Expression of Merlin protein in non-small cell lung carcinoma and the clinical significance / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 565-569, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-814548
ABSTRACT
OBJECTIVE@#To determine the expression and clinical significance of Merlin protein in non-small cell lung cancer (NSCLC).@*METHODS@#The expression of Merlin protein in 45 cases of NSCLC and adjacent tissue of NSCLC and normal lung tissue was checked by immunohistochemistry. The relation between the expression of Merlin protein and the multiple factors of pathological type, gender, P-TNM stage, differentiation and lymph node metastasis was analyzed.@*RESULTS@#The expression rates of Merlin protein in NSCLC and normal lung tissue sections were 73.33% and 15.56%, respectively (P0.05).@*CONCLUSION@#Merlin protein might contribute to the initiation of metastasis of NSCLC.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Physiology
/
Genes, Neurofibromatosis 2
/
Carcinoma, Non-Small-Cell Lung
/
Neurofibromin 2
/
Lung Neoplasms
/
Metabolism
/
Neoplasm Metastasis
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2011
Type:
Article
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