Case-control study on environmental factors in congenital heart disease / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 159-164, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-814589
ABSTRACT
OBJECTIVE@#To explore the relation between environmental factors and the occurrence of congenital heart disease (CHD).@*METHODS@#A hospital-based case-control study was conducted. Mothers of 123 patients with congenital heart disease and 246 normal newborns were interviewed with standardized questionnaires. Chi-square test and logistic regression models were performed to analyze the influencing factors.@*RESULTS@#As shown in multivariable logistic model, gravida with occupational exposure (OR=4.10), or gravida with chronic diseases during progestational pregnancy (OR=5.95), gravida with abnormal childbearing history (OR=6.27), and gravida catching a cold in the early stage of pregnancy (OR=2.07) would increase the risk of CHD. On the contrary, eating meat, egg (OR=0.18) and milk (OR=0.23), and taking multivitamin and microelement (OR=0.35) during the pregnancy reduced the risk of CHD.@*CONCLUSION@#The risk of the offspring developing CHD is associated with gravida's exposure to many environmental factors during pregnancy. It is time to strengthen the intervention measures to reduce the occurrence of CHD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pregnancy Complications
/
Prenatal Exposure Delayed Effects
/
Case-Control Studies
/
Logistic Models
/
Surveys and Questionnaires
/
Risk Factors
/
Occupational Exposure
/
Maternal Nutritional Physiological Phenomena
/
Environment
/
Heart Defects, Congenital
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Infant, Newborn
/
Pregnancy
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2011
Type:
Article
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