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A clinical analysis of 96 patients with bloodstream infections after solid organ transplantation / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences) ; (12): 509-512, 2012.
Article in Chinese | WPRIM | ID: wpr-814637
ABSTRACT
OBJECTIVE@#To evaluate clinical characteristics, pathogens, treatment regimens and outcomes in patients with bloodstream infections (BSIs) after solid organ transplantation.@*METHODS@#Clinical data of ninety six cases of BSI were analyzed retrospectively to identify the pathogens and the origin of infection, and to evaluate comprehensive treatment and the causes of success or failure.@*RESULTS@#All 96 patients underwent the comprehensive treatments, including suspending administration of immunosuppressants and starting administration of appropriate antibiotics. The clinical characteristics of patients with BSIs after solid organ transplantation were atypical. The pathogens were various and seriously multi-drug resistant, which led to a high mortality. Among them 57 cases recovered, but the BSI-related mortality rate was 40.6%.@*CONCLUSION@#Stopping the administration of immunosuppressants, reasonable use of antibiotics, nutritional support and protecting the function of organs as soon as possible were of the greatest importance among of the various treatment plan. Avoidance of all kinds of infection in the first place is most important.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Retrospective Studies / Kidney Transplantation / Liver Transplantation / Gram-Positive Bacterial Infections / Gram-Negative Bacterial Infections / Combined Modality Therapy / Sepsis / Therapeutic Uses / Drug Therapy / Microbiology Type of study: Observational study / Prognostic study Limits: Adolescent / Adult / Child / Female / Humans / Male Language: Chinese Journal: Journal of Central South University(Medical Sciences) Year: 2012 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Retrospective Studies / Kidney Transplantation / Liver Transplantation / Gram-Positive Bacterial Infections / Gram-Negative Bacterial Infections / Combined Modality Therapy / Sepsis / Therapeutic Uses / Drug Therapy / Microbiology Type of study: Observational study / Prognostic study Limits: Adolescent / Adult / Child / Female / Humans / Male Language: Chinese Journal: Journal of Central South University(Medical Sciences) Year: 2012 Type: Article