A case of lipoprotein glomerulopathy and a literature review of the subject / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 320-324, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-814676
ABSTRACT
To improve the understanding of lipoprotein glomerulopathy, the clinical data of a single case of lipoprotein glomerulopathy, diagnosed at the Second Xiangya Hospital, Central South University in June 2011, were retrospectively analyzed. The analysis included clinical manifestation, laboratory results, and pathological information on kidney biopsy. Nephrotic syndrome was seen as the major clinical feature in this patient. Levels of serum apoE and apoB were increased. Obvious expansion of glomerular capillary cavities, filled with a weakly stained thrombus-like substance, were observed. ApoE immunohistochemical staining showed positive staining in capillary luminal contents. Transmission electron microscopy revealed capillary lumina occluded by various foaming lipid depositions in clustered or layered arrangement. There were no special symptoms nor obvious abnormal laboratory results of the LPG patient. Diagnosis of LPG should be based on clinical manifestations and renal biopsy. Characteristic pathological performance plays an important role in the diagnosis of lipoprotein glomerulopathy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Biopsy, Needle
/
Diagnosis
/
Kidney
/
Kidney Diseases
Type of study:
Diagnostic study
Limits:
Adult
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2012
Type:
Article
Similar
MEDLINE
...
LILACS
LIS