Correlation between ABCC11 gene single nucleotide polymorphism and the incidence of axillary osmidrosis in Chinese Han population / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 1141-1145, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-814810
ABSTRACT
OBJECTIVE@#To explore the relationship between ABCC11 gene single nucleotide polymorphism (SNP) and the incidence of axillary osmidrosis in Chinese Han population.@*METHODS@#The genotype of ABCC11 gene SNP at rs17822931 in 40 patients with axillary osmidrosis and 5 normal Han people was detected and analyzed by high resolution melt and gene sequencing.@*RESULTS@#The detection of the genotype of ABCC11 gene SNP at rs17822931 showed that 37 of the 40 patients were GA genotype and the other 3 were GG genotype, while the 5 normal subjects were AA genotype.@*CONCLUSION@#SNP in ABCC11 is the genetic cause of axillary osmidrosis. GG or GA leads to axillary osmidrosis, while AA allele presents the absence of axillary osmidrosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Axilla
/
Sweat Gland Diseases
/
Incidence
/
ATP-Binding Cassette Transporters
/
Polymorphism, Single Nucleotide
/
Asian People
/
Alleles
/
Gene Frequency
/
Genetics
/
Genotype
Type of study:
Incidence study
/
Prognostic study
Limits:
Humans
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2013
Type:
Article
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