8.5 year-follow-up of combined heart-lung transplantation in a patient / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 212-215, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-814898
ABSTRACT
To summarize the case of combined heart-lung transplantation for a patient who survived for 8.5 years. On September 20, 2003, at Second Xiangya Hospital of Central South University, homologous heartlung transplantation was performed on a male patient who was diagnosed with cardiopulmonary failure secondary to congenital ventricular septal defect with severe pulmonary hypertension. Heart-lung allograft was preserved with 1500 mL modified St.Thomas solution and 3000 mL modified LPD solution. Postoperative immunosuppressive therapies included methylprednisolone and human anti-lymphocyte globulin protein in the induction period; and combination of ciclosporin A, CellCept and prednisolone in the stable period. In 2007, the treatment was changed to CellCept mg, twice a day+FK506 4 mg, twice a day. The patient lived 8.5 years of normal life with cardiac function of NYHA I-II. Echocardiogram showed left ventricular ejection fraction of 61% to 74%. Heart-lung transplantation proved reliable therapy modality for terminal cardiopulmonary failure. Excellent donor organ preservation and proper perioperative treatment are key factors for long-term survival after heart-lung transplantation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
General Surgery
/
Follow-Up Studies
/
Heart-Lung Transplantation
/
Therapeutic Uses
/
Eisenmenger Complex
/
Graft Rejection
/
Heart Septal Defects, Ventricular
/
Hypertension, Pulmonary
/
Immunosuppressive Agents
/
Methods
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
/
Male
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2013
Type:
Article
Similar
MEDLINE
...
LILACS
LIS