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Effect of acitretin and methotrexate on treatment of 
severe plaque psoriasis / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences) ; (12): 804-808, 2016.
Article in Chinese | WPRIM | ID: wpr-814960
ABSTRACT
OBJECTIVE@#To evaluate effects of acitretin and methotrexate on treatment of severe plaque psoriasis.
@*METHODS@#A total of 54 patients were treated with either acitretin (32 patients; 30 mg per day) or methotrexate (22 patients; 15 mg per week) for 8 weeks. The therapeutic effects of the two drugs were evaluated according to the psoriasis area and severity index (PASI).
@*RESULTS@#After 8 weeks of treatment, the score of PASI decreased in both the acitretin group and the methotrexate group (P0.05).
@*CONCLUSION@#Acitretin and methotrexate exert similar therapeutic effect in severe plaque psoriasis.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Psoriasis / Methotrexate / Acitretin Limits: Humans Language: Chinese Journal: Journal of Central South University(Medical Sciences) Year: 2016 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Psoriasis / Methotrexate / Acitretin Limits: Humans Language: Chinese Journal: Journal of Central South University(Medical Sciences) Year: 2016 Type: Article