Role of local citrate anticoagulation in continuous blood purification to patients at high risk of bleeding in ICU / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 1334-1339, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-815088
ABSTRACT
To evaluate the safety and efficiency of citrate anticoagulant-based continuous blood purification in patients at high risk of bleeding.
Methods:
One hundred and fifty-two patients at high risk of bleeding were divided into local citrate group (group A, n=68) and heparin group (group B, n=84). Clotting function, change of pH, ionized sodium, bicarbonate ion, ionized calcium, activated clotting time (ACT) and complications were monitored before and during treatment.Results:
Compared to the group A, the incidence of clotting in filter and chamber, the degree of bleeding or fresh bleeding were significantly reduced in the group B (P0.05). The pH value, the levels of ionized sodium, bicarbonate ion and ionized calcium during the treatment were maintained in normal range in both group A and group B.Conclusion:
Local citrate-based continuous blood purification can achieve effective anticoagulation and decrease the incidence of bleeding. It is an ideal choice for patients at high risk of bleeding.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Reference Values
/
Sodium
/
Bicarbonates
/
Blood
/
Blood Coagulation
/
Blood Coagulation Tests
/
Heparin
/
Calcium
/
Renal Dialysis
Type of study:
Etiology study
Limits:
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2016
Type:
Article
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