Expression of lactate dehydrogenase-5 in non-Hodgkin lymphoma and its clinical significance / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 1312-1316, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-815092
ABSTRACT
To determine expression of lactate dehydrogenase (LDH)-5 in non-Hodgkin lymphoma and its clinical significance.
Methods:
LDH-5 levels and LDH levels in NHL patients were examined by agarose gel electrophoresis and enzymatic method (n=63), respectively. Positive rates of LDH-5 and LDH were statistically analyzed.Results:
The median age of NHL patients was 56(19-84) years old, including 36 males and 27 females. The positive numbers for LDH-5 and LDH in the initial treatment group (n=43) were significantly different (P0.05). In 15 cases under the status of progress, the difference of LDH-5 and LDH expressions were not significant (P>0.05), whereas the difference in cases of small B cell lymphoma was significant (P<0.05).Conclusion:
LDH-5 can be used as an index for NHL to judge the tumor load and to predict the recurrence.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Blood
/
Lymphoma, Non-Hodgkin
/
Biomarkers, Tumor
/
Lymphoma, B-Cell
/
Lymphoma, T-Cell
/
Lymphoma, Large B-Cell, Diffuse
/
Tumor Burden
/
Lactate Dehydrogenase 5
/
Genetics
Type of study:
Prognostic study
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2016
Type:
Article
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