Efficacy of R±BEACOP regimen in patients with
poor-prognosis lymphoma / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 858-863, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-815258
ABSTRACT
OBJECTIVE@#To analyze the efficacy of cyclophosphamideplus, epirubicin, vincristine, prednisone plus etoposide and/or bleomycin, with or without rituximab (R±BEACOP) regimen in patient with poor-prognosis lymphoma.
@*METHODS@#A total of 89 patients, who had poor-prognosis lymphoma and received at least 1 cycle of R±BEACOP regimen during 2002 to 2012, were enrolled and analyzed by a retrospective study.
@*RESULTS@#The rate of complete response was 62.9% (56 patients). The efficacy of Hodgkin lymphoma (HL) and T/NK NHL was better than that of other types of lymphoma. There was no significant difference in efficacy among the patients with different age, stage or international prognosis index (IPI) (all P>0.05).
@*CONCLUSION@#R±BEACOP regimen is effective in some patients with poor prognosis, especially in HL patients. Thus, multicenter prospective study regarding the R±BEACOP regimen needs to be done to further test its efficacy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Procarbazine
/
Prognosis
/
Vincristine
/
Bleomycin
/
Prednisone
/
Antineoplastic Combined Chemotherapy Protocols
/
Doxorubicin
/
Retrospective Studies
/
Classification
/
Cyclophosphamide
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Humans
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2015
Type:
Article
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