A better knowledge of the relationship between osteoarthritis and osteoporosis may help the stratification treatment / 中国实用内科杂志

ABSTRACT

TO understand the relationship between osteoarthritis(OA) and osteoporosis as well as the subtypes of OA may pave the way for patient stratification and the development of precision medicines for OA. Osteoporosis(OP) may cause OA development,while OA patients have higher risk for fracture. Abnormal subchondral bone remodeling and subsequent microstructural damage is key pathogenesis of osteoporotic OA. Bone-acting agents, such as bisphosphonate, may be a new choice for osteoporotic OA.