Clinical analysis of 7 cases of Fanconi syndrome sencondary to Sjogren's syndrome / 中国实用内科杂志
Chinese Journal of Practical Internal Medicine
;
(12): 909-912, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-816125
ABSTRACT
OBJECTIVE:
To investigate the clinical characteristics of patients with Fanconi syndrome(FS)sencondary to Sjogren's syndrome(SS).METHODS:
The clinical data of 7 patients with FS secondary to SS were retrospectively analyzed. The clinical manifestations, auxiliary examinations, treatment options and curative effects were analyzed.RESULTS:
Besides xerostomia and xerophthalmia, fatigue, polyuria and bone pain were found in 7 patients. Osteoporosis occurred in 6 cases and renal insufficiency in 3 cases. Immunoglobulin was increased in 7 cases, including 7 with IgG increase and 4 with IgG, IgA and IgM increase. All patients showed different degrees of ionic disorder and vitamin D deficiency. Renal glycosuria and amino acid urine were found in all 7 patients. All patients were treated with glucocorticoid combined with immunosuppressive agents. At the same time,they were treated with maintenance of acid-base and electrolyte balance and supplementation of active vitamin D. The curative effect was good.CONCLUSION:
FS secondary to SS is rare, and patients are more prone to osteoporosis and renal insufficiency. Early diagnosis and treatment are essential.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Screening study
Language:
Chinese
Journal:
Chinese Journal of Practical Internal Medicine
Year:
2019
Type:
Article
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