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The Efficacy of 99mTc-DMSA SPECT in Diagnosis of Renal Scarringn of Vesicoureteral Reflux in Children / 대한비뇨기과학회지
Korean Journal of Urology ; : 627-632, 1998.
Article in Korean | WPRIM | ID: wpr-81652
ABSTRACT

PURPOSE:

The diagnosis of renal scarring is very important for the pediatric patient because it has been associated with the later development of hypertension, renal failure, and end-stage kidney disease. Recent studies indicate that the sensitivity and specificity of the99mTc-DMSA single photon emission computerized tomography (SPECT) is better than IVP, USG, and 99mTC-DMSA Planar ThG Purpose Of this Study iS tO Compare 2 types Of 9%nTh DMSA renal scan(planar and SPECT) and IVP/USG in the diagnosis of renal scars. MATERIALS AND

METHOD:

We reviewed retrospectively the data of 49 children(72 renal units) with vesicoureteral reflux(VUR) who underwent renal cortical imaging with IVP/USG from January 1987 to August 1996. Patient ages ranged from 3 months to 14 years with a mean age 3.7 years. There were 17 boys and 12 girls(44 venal units) with 99mTc-DMSA planar with IVP/USG, and 12 boys and 8 girls(28 renal units) with 99mTc-DMSA SPECT with IVP/USG.

RESULTS:

The 99mTc-DMSA planar imaging identified 94.7% sensitivities while 99mTC-DMSA SPECT imaging identified 96.3% Sensitivities. And the IVP/USG identified 75.3% sensitivities.

CONCLUSIONS:

Recently, the 99mTc-DMSA renal scan has replaced IVP/USG in detecting renal scarring. And we show that 99mTc-DMSA SPECT studies are superior to IVP/USG, 99mTc-DMSA planar studies in detecting renal scarring. We believe that the role of 99mTc-DMSA SPECT will become increasingly important in detecting renal scarring of VUR.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Vesico-Ureteral Reflux / Tomography, Emission-Computed, Single-Photon / Retrospective Studies / Sensitivity and Specificity / Cicatrix / Succimer / Technetium Tc 99m Dimercaptosuccinic Acid / Diagnosis / Hypertension, Renal / Kidney Failure, Chronic Type of study: Diagnostic study / Observational study Limits: Child / Humans Language: Korean Journal: Korean Journal of Urology Year: 1998 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Vesico-Ureteral Reflux / Tomography, Emission-Computed, Single-Photon / Retrospective Studies / Sensitivity and Specificity / Cicatrix / Succimer / Technetium Tc 99m Dimercaptosuccinic Acid / Diagnosis / Hypertension, Renal / Kidney Failure, Chronic Type of study: Diagnostic study / Observational study Limits: Child / Humans Language: Korean Journal: Korean Journal of Urology Year: 1998 Type: Article