Isolation and Identification the Compositions of Alkaloids in Acorus tatarinowii / 中国药房
China Pharmacy
;
(12): 642-645, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-817066
ABSTRACT
OBJECTIVE: To isolate and identify the compositions of alkaloids in Acorus tatarinowii, and to lay the foundation for further study of its pharmacological activity. METHODS: The compositions of alkaloids from A. tatarinowii was separated by cation exchange resin. UPLC-MS method was used to identify the alkaloids. The separation was performed on a Agilent Zorbax Eclipse Plus-C18 column with mobile phase consisted of 0.1% formic acid-acetonitrile (gradient elution) at a flow rate of 0.3 mL/min. The column temperature was 30 ℃, and the injection volume was 1 μL. ESI ion source was used to detect the fragments, the ion mode scan was positive. Peakview 1.2 and other softwares were used to analyze the compositions of alkaloids. RESULTS: 86 compositions were separated and 5 alkaloids were identified, such as tatarine A, N-trans-feruloyltyramine, N-lauryldiethanolamine, phytosphingosine and 5-butyluridine. CONCLUSIONS: The results of the study lay a foundation for the study of pharmacological activity of alkaloids from A. tatarinowii.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2019
Type:
Article
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