Advance in the Monitoring and Treatment of Sepsis-Induced Immunosuppression / 中山大学学报(医学科学版)
Journal of Sun Yat-sen University(Medical Sciences)
;
(6): 30-36, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-817629
ABSTRACT
@#Sepsis is defined as a life- threatening organ dysfunction caused by a deregulated host response to infection and is the leading cause of mortality in intensive care units. Although the exact pathogenesis of sepsis remains unclear,immunosuppression is considered to play a key role. Sepsis-induced immunosuppression is characterized by a failure to eradicate the primary infection and by development of secondary nosocomial infections, resulting in a prolonged hospitalization and increased death rate in sepsis patients. Early recognition of immunosuppression and appropriate intervention will benefit these patients. This review helps clinicians identify patients with immunosuppression through high-risk population screening and biomarkers detection,and introduces immunostimulants that have been used in clinics and clinical trials.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Sun Yat-sen University(Medical Sciences)
Year:
2020
Type:
Article
Similar
MEDLINE
...
LILACS
LIS