DestructionandProtectionStrategyofBlood-brainBarrierDuringIschemicStroke / 中山大学学报(医学科学版)
Journal of Sun Yat-sen University(Medical Sciences)
;
(6): 641-647, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-817676
ABSTRACT
@#Blood-brainbarrier（BBB），abarrierstructurebasedonbrainmicrovascularendothelialcells，playsan importantroleinmaintainingthehomeostaticmicroenvironmentofcentralnervoussystem（CNS）.Underthepathological conditionsofischemicstroke，localinflammationandchangesinthestatusandstructureofcellsleadtoBBBdisruption. AsaresultofBBBpermeabilityrising，variousbloodcomponents，especiallyactivatedinflammatorycellsorinflammatory factors，passthroughthedamagedBBBtoreachcerebralinfarctionareaandaggravatebraininjury.Thisarticlereviews themechanismofBBBdisruptionbythefunctionofactivatedcellsclusteredininfarctionareaafterischemicstrokeand brieflysummarizesourteam′scurrentworkonrepairingBBBinjuries.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Sun Yat-sen University(Medical Sciences)
Year:
2019
Type:
Article
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