Risk Factors and Scoring System Evaluation of Long-Term Cardiovascular Adverse Events after Bleeding among Patients with Coronary Heart Disease / 中山大学学报(医学科学版)

ABSTRACT

@#【Objective】 To investigate the risk factors of long- term adverse cardiovascular outcomes for coronary artery disease patients after gastrointestinal bleeding and evaluate the value of AIMS65 score and Glasgow- Blatchford score（GBS） for predicating these outcomes among those patients.【Methods】 All coronary artery disease patients with gastrointestinal bleeding were enrolled in the study from 2014 to 2016. All demographic data and clinical data for hospitalized coronary artery disease patients with gastrointestinal bleeding were retrospectively analyzed and all patients were divided into two groups according to whether the main outcomes occurred or not in order to detect their clinical features ， risk factors，and the prediction value of two score systems.【Results】Seventy patients showed the adverse cardiovascular outcomes among all patients. The area under the curve（AUC）that AIMS65 and GBS predicate the main outcomes were 0.59（P=0.035）and 0.51（P=0.039），respectively. The result of univariate analysis showed that age ，diabetes ，prior myocardial infarction ，hemoglobin ，prior proton- pump inhibitor use during hospital stay and blood transfusion were the risk factors. After multivariate analysis ，anemia ，high blood pressure and diabetes are independent risk factors.【Conclusions】 The GBS and AIMS65 both have a low specificity and sensitivity. Anemia ，high blood pressure and diabetes are independent risk factors of adverse cardiovascular outcomes after gastrointestinal bleeding.