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Simultaneously detect three illegal additive components in Yinhuang soft capsule by TLC-SERS / 药学实践杂志
Article in Zh | WPRIM | ID: wpr-817809
Responsible library: WPRO
ABSTRACT
Objective To establish a simultaneous detection of diclofenac sodium, fenbufen and rotundine hydrochloride illegally added in Yinhuang soft capsules by TLC-SERS. Methods The samples to be measured were placed on the silica gel plate, and the thin layer was developed with petroleum ether-ethyl acetate (3:5). Location detection was carried out under 254 nm ultraviolet lamp. Nano-silver colloidal solution was sprayed at each spot of separation according to the optimum conditions, and then qualitative identification was done by TLC-SERS. Results A method for simultaneous determination of diclofenac sodium, fenbufen and rotundine hydrochloride illegally added in Yinhuang soft capsule by TLC-SERS was established. And the minimum detection limits of three chemical constituents were determined. Conclusion TLC-SERS was a rapid, accurate and sensitive method for the simultaneous and rapid detection of diclofenac sodium, fenbufen and rotundine hydrochloride illegally added into Yinhuang soft capsule.
Key words
Full text: 1 Index: WPRIM Type of study: Qualitative_research Language: Zh Journal: Journal of Pharmaceutical Practice Year: 2020 Type: Article
Full text: 1 Index: WPRIM Type of study: Qualitative_research Language: Zh Journal: Journal of Pharmaceutical Practice Year: 2020 Type: Article