Simultaneously detect three illegal additive components in Yinhuang soft capsule by TLC-SERS / 药学实践杂志
Journal of Pharmaceutical Practice
; (6): 166-169, 2020.
Article
in Zh
| WPRIM
| ID: wpr-817809
Responsible library:
WPRO
ABSTRACT
Objective To establish a simultaneous detection of diclofenac sodium, fenbufen and rotundine hydrochloride illegally added in Yinhuang soft capsules by TLC-SERS. Methods The samples to be measured were placed on the silica gel plate, and the thin layer was developed with petroleum ether-ethyl acetate (3:5). Location detection was carried out under 254 nm ultraviolet lamp. Nano-silver colloidal solution was sprayed at each spot of separation according to the optimum conditions, and then qualitative identification was done by TLC-SERS. Results A method for simultaneous determination of diclofenac sodium, fenbufen and rotundine hydrochloride illegally added in Yinhuang soft capsule by TLC-SERS was established. And the minimum detection limits of three chemical constituents were determined. Conclusion TLC-SERS was a rapid, accurate and sensitive method for the simultaneous and rapid detection of diclofenac sodium, fenbufen and rotundine hydrochloride illegally added into Yinhuang soft capsule.
Full text:
1
Index:
WPRIM
Type of study:
Qualitative_research
Language:
Zh
Journal:
Journal of Pharmaceutical Practice
Year:
2020
Type:
Article