Research progresses of inflammasome in the pathogenesis of acute pancreatitis / 医学研究生学报
Journal of Medical Postgraduates
;
(12): 1228-1232, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-818173
ABSTRACT
Acute pancreatitis (AP) is a common clinical emergency. Aseptic inflammation caused by the death of acinar cells is the early pathological change of AP. However, the main mechanism of aggravation of AP is the subsequently excessive inflammation which leads to multiple organ dysfunctions. Among them, the assembly and activation of inflammatory corpuscles are involved in the pathogenesis. It has shown that metabolic regulation of inflammatory corpuscle activation and its regulatory effectors play an important and decisive role in AP and its inflammatory response mechanism. This article reviews the structure and function of inflammasomes and their role in the pathogenesis of AP.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
Chinese
Journal:
Journal of Medical Postgraduates
Year:
2019
Type:
Article
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