Research progress of MSCs-derived exosomes carrying miRNAs in the repair of cartilage degeneration / 医学研究生学报
Journal of Medical Postgraduates
;
(12): 1312-1317, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-818189
ABSTRACT
The incidence of cartilage degeneration (osteoarthritis, etc.) is increasing year by year, putting heavy pressure on families and society. It has become a consensus that mesenchymal stem cells can repair damaged cartilage. As the research progresses, more and more evidence indicates that its effects are attributed to the paracrine system, especially the exosomes. Exosomes are a lipid bilayer cystic structure encapsulating biologically active factors such as proteins, lipids, mRNA, and microRNAs (miRNAs/miRs), which can regulate the biological functions of cells. As a signal and carrier for transmitting important information between cells, it plays a very important role in the repair of cartilage degeneration damage. This paper reviews the research of mesenchymal stem cell-derived exosomes carrying miRNAs in the repair of cartilage injury.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Medical Postgraduates
Year:
2019
Type:
Article
Similar
MEDLINE
...
LILACS
LIS