The research progress for the role of platelet in sepsis and anti⁃platelet therapy / 医学研究生学报
Journal of Medical Postgraduates
;
(12): 196-200, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-818211
ABSTRACT
The clinical treatment of sepsis has always been a problem. Sepsis is characterized by high morbidity, high mortality and high treatment costs.Platelets were previously thought to play a major role in hemostasis and thrombosis.In recent years, it has been found that platelets are very important in inflammation and immune regulation as well as in hemostasis and thrombosis. Antiplatelet therapy can reduce release of inflammation and immunomodulatory mediators by attenuating platelet activation, thereby alleviating the inflammatory response in sepsis. This paper reviews the mechanism of platelet involvement in sepsis and the clinical progress of antiplatelet drugs in managing sepsis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Medical Postgraduates
Year:
2019
Type:
Article
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