Advances in research on the function and disease of desmoglein 2 / 医学研究生学报
Journal of Medical Postgraduates
;
(12): 540-545, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-818276
ABSTRACT
Desmoglein (DSG) is an important constituent of desmosome, a single transmembrane glycoprotein that binds to desmocollin (DSC), regulates intercellular adhesion and transmits intracellular and extracelluar signals. Studies have shown that DSG2, one subtype of the DSG, is abnormally expressed in tumor cells and has certain value for targeted treatment and prognosis. This paper reviews the structure, biological functions and related diseases of DSG2 protein.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Medical Postgraduates
Year:
2019
Type:
Article
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