Diagnosis and differential diagnosis of autoimmune hepatitis / 临床肝胆病杂志

ABSTRACT

Autoimmune hepatitis (AIH) is a chronic persistent liver inflammatory disease associated with autoimmune response. AIH is commonly seen in women, and those without intervention may progress to liver cirrhosis and liver cancer. The main histological feature of AIH is moderate to severe interfacial hepatitis with lymphocyte-plasma cell infiltration. The clinical manifestations of AIH have obvious heterogeneity, and it is difficult to differentiate AIH from other liver diseases with similar clinical, biochemical, serological, and histological features. Misdiagnosis may seriously affect the prognosis of patients. This article reviews the key points in the diagnosis and differential diagnosis of AIH, hoping to provide help for clinical diagnosis and treatment.