Study on serum cytokine levels in posttraumatic stress disorder patients
Asian Pacific Journal of Tropical Medicine
; (12): 323-325, 2012.
Article
in En
| WPRIM
| ID: wpr-819777
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#To evaluate serum IL-2, IL-4, IL-6, IL-8, IL-10 and TNF-α levels in posttraumatic stress disorder (PTSD) patients.@*METHODS@#We utilized ELISA technology to examine cytokines such as IL-2, IL-4, IL-6, IL-8, IL-10 and TNF-α in serum from 50 well-characterized individuals with a primary DSM-IV PTSD diagnosis, and 50 age- and gender-matched healthy controls. We conservatively employed a Mann-Whitney U testing.@*RESULTS@#Individuals with primary PTSD had significantly elevated peripheral cytokine levels for all 6 different cytokines compared to age- and gender-matched healthy controls (all P<0.01).@*CONCLUSIONS@#These findings suggest that a generalized inflammatory state may be present in individuals with PTSD.
Full text:
1
Index:
WPRIM
Main subject:
Stress Disorders, Post-Traumatic
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Blood
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Enzyme-Linked Immunosorbent Assay
/
Case-Control Studies
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Interleukins
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Tumor Necrosis Factor-alpha
/
Metabolism
Type of study:
Observational_studies
Limits:
Adult
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Female
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Humans
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Male
Language:
En
Journal:
Asian Pacific Journal of Tropical Medicine
Year:
2012
Type:
Article