Effect of Alpinia officinarum Hance alcohol extracts on primary dysmenorrheal
Asian Pacific Journal of Tropical Medicine
;
(12): 882-886, 2016.
Article
in English
| WPRIM
| ID: wpr-819898
ABSTRACT
OBJECTIVE@#To study the effect of Alpinia officinarum Hance (A. officinarum) 80% alcohol extract on the primary dysmenorrhea.@*METHODS@#A. officinarum 80% alcohol extract were enriched by macroporous adsorption resins. Female mice of primary dysmenorrhea model were established by oxytocin induction; the effects of A. officinarum 80% alcohol extract on primary dysmenorrhea were observed by body twist method; and the homogenate level of prostaglandin F2α (PGF2α), prostaglandin E2 (PGE2) and Ca(2+) in the uterus were observed in oxytocin-induced female mice.@*RESULTS@#The writhing frequency of primary dysmenorrhea mice was significantly decreased after treatment of A. officinarum 80% alcohol extract and the level of PGF2α, PGE2 and Ca(2+) in mice uterus was significantly decreased (P < 0.05, P < 0.01) in groups of mice treated with middle and high dosage of A. officinarum 80% alcohol extract compared with that of model group.@*CONCLUSIONS@#These findings suggest that A. Officinarum 80% alcohol extract can significantly relieve primary dysmenorrhea.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Asian Pacific Journal of Tropical Medicine
Year:
2016
Type:
Article
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