Your browser doesn't support javascript.
loading
Correlation of chronic periodontitis in tropical area and IFN-γ, IL-10, IL-17 levels
Asian Pacific Journal of Tropical Medicine ; (12): 489-492, 2013.
Article in English | WPRIM | ID: wpr-820015
ABSTRACT
OBJECTIVE@#To evaluate the correlation of chronic periodontitis in tropical area and IFN-γ, IL-10 and IL-17 levels.@*METHODS@#One hundred and forty-eight patients and one hundred and thirty-two healthy control subjects were included in the study. Clinical parameters (PI, GI and PD) and GCF levels of IFN-γ, IL-10 and IL-17 were measured at baseline, week 8, week 16 and week 24 after mechanical removal of dental plaque. IFN-γ and IL-10 were determined with ELISA methods and IL-17 was determined with the cytometric bead array.@*RESULTS@#Removal of dental plaque resulted in improvement in all clinical parameters. Meanwhile, GCF IL-17 declined to control levels, while GCF IFN-γ and IL-10 levels remained unchanged.@*CONCLUSIONS@#The decline of GCF IL-17 levels in patients with resolution of periodontitis suggests that IL-17 is involved in the periodontal inflammatory process.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Therapeutics / Tropical Climate / Case-Control Studies / Chemistry / China / Epidemiology / Gingival Crevicular Fluid / Dental Scaling / Interferon-gamma / Interleukin-10 Type of study: Observational study / Risk factors Limits: Adult / Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Asian Pacific Journal of Tropical Medicine Year: 2013 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Main subject: Therapeutics / Tropical Climate / Case-Control Studies / Chemistry / China / Epidemiology / Gingival Crevicular Fluid / Dental Scaling / Interferon-gamma / Interleukin-10 Type of study: Observational study / Risk factors Limits: Adult / Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Asian Pacific Journal of Tropical Medicine Year: 2013 Type: Article