Effect of wheat grass powder on aluminum induced Alzheimer's disease in Wistar rats
Asian Pacific Journal of Tropical Medicine
;
(12): S278-81, 2014.
Article
in English
| WPRIM
| ID: wpr-820211
ABSTRACT
OBJECTIVE@#To find out the effect of wheat grass on aluminum induced Alzheimer's disease in Wistar rats.@*METHODS@#Memory impairment was induced by aluminum chloride (4.2 mg/kg, i.p.) for 28 d. Memory function was assessed by Morris water maze test. To study the activity of wheat grass (100 mg/kg, p.o.), Wistar rats were administered it for 28 d along with aluminum chloride. Biochemical parameters of oxidative stress were estimated in brain after the treatment.@*RESULTS@#The major finding of this study is that aluminum enhanced oxidative stress. Wheat grass showed a significant improvement in reduction of this oxidative stress by reduction of malondialdehyde levels and enhancement of superoxide dismutase and catalase levels.@*CONCLUSIONS@#The present study clearly demonstrated the beneficial effects of wheat grass that shows good antioxidant properties, and this remarkable effect of wheat grass may act as a key to treat Alzheimer's disease.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Asian Pacific Journal of Tropical Medicine
Year:
2014
Type:
Article
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