Characterization of two Achromobacter xylosoxidans isolates from patients with pertussis-like symptoms
Asian Pacific Journal of Tropical Medicine
;
(12): 464-467, 2015.
Article
in English
| WPRIM
| ID: wpr-820332
ABSTRACT
OBJECTIVE@#To characterize two Achromobacter xylosoxidans recovered from 2 patients diagnosed with pertussis during a Bordetella pertussis surveillance program.@*METHODS@#Nasopharyngeal swabs from 2 children under 1 year of age with clinical suspicion of pertussis were analyzed by culture and PCR.@*RESULTS@#Two Achromobacter xylosoxidans A8, closely related to Bordetella spp. were recovered from 2 patients diagnosed of pertussis, both carrying the ptxA gene and IS418 the pertussis toxin encoding gene. Subsequently, antibiotic susceptibility was evaluated by disk-diffusion method and by PCR.@*CONCLUSIONS@#Although more detailed studies are needed, the present data highlight the possibility that Achromobacter xylosoxidans, closely related Bordetella pertusssis microorganisms and not covered under the vaccine umbrella, might also result in cases of whooping cough. Thereby further surveillance is necessary to determine the extension and relevance of their pathogenic role in order to discriminate their real public health implication.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
English
Journal:
Asian Pacific Journal of Tropical Medicine
Year:
2015
Type:
Article
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